Publications

Hananya N., Eldar-Boock A., Bauer CR., Satchi-Fainaro R., Shabat D., Remarkable Enhancement of Chemiluminescent Signal by Dioxetane-Fluorophore Conjugates: Turn-ON Chemiluminescence Probes with Color Modulation for Sensing and Imaging, J. Am. Chem. Soc., 2016, 138, 13438-46.

Gasser V., Baco E., Cunrath O., Sain-Auguste P., Perraud Q., Zill N., Schleberger C., Schmidt A., Paulen A., Bumann D., Mislin G.L.A., Schalk I. J. The switch off of the enterobactin iron uptake pathway in Pseudomonas cells grown in the presence of catechol vectors : an asset for Tojan horse antibiotherapy strategy. Environm. Microbiol., 2016, 18(3):819-32.

Klahn P., Brönstrup M.. Bifunctional antimicrobial conjugates and hybrid antimicrobials. Natural Product Reports, 2017, 34, 832-885. doi: 10.1039/c7np00006e

Ferreira K., Hu H.-Y., Fetz V., Prochnow H., Rais B., Müller P.P., Brönstrup M., Multivalent Siderophore–DOTAM Conjugates as Theranostics for Imaging and Treatment of Bacterial Infections. Angewandte Chemie International Edition, 2017, 56, 28, 8272-8276. doi: 10.1002/anie.201701358

Green O., Eilon T., Hananya N., Gutkin S., Bauer CR., Shabat D. Opening a Gateway for Chemiluminescence Cell Imaging: Distinctive Methodology for Design of Bright Chemiluminescent Dioxetane Probes, ACS Central Sci., 2017, 4, 349-58.

Paulen A., Hoegy F., Roche B., Schalk I.J., Mislin G.L.A. Synthesis of conjugates between oxazolidinone antibiotics and a pyochelin analogue. Bioorg. Med. Chem. Lett., 2017, 27, 4867-4870.

Schalk I. J., Mislin G. L. A. Bacterial Iron Uptake Pathways: Gates for the Import of Bactericide Compounds. J Med Chem., 2017, 60, 4573-4576.

Gnaim S., Shabat D., Self-Immolative Chemiluminescence Polymers: Innate Assimilation of Chemiexcitation in a Domino-Like Depolymerization, J. Am. Chem. Soc., 2017, 139, 10002-08.

Hananya N, Green, O., Blau, R., Satchi-Fainaro, R., Shabat, D. A Highly-Efficient Chemiluminescence Probe for Detection of Singlet Oxygen in Living Cells, Angew. Chem. Int. Ed. 2017, 56, 11793-96.

Green O., Gnaim S., Blau R., Eldar-Boock A., Satchi-Fainaro R., Shabat D., Near-Infrared Dioxetane Luminophores with Direct Chemiluminescence Emission Mode, J. Am. Chem. Soc., 2017, 139, 13242-48.

Hananya N., Shabat D., A Glowing Trajectory between Bio- and Chemi-Luminescence: From Luciferin-based Probes to Triggerable Dioxetanes, Angew. Chem. Int. Ed. 2017, 56, 16454-63.

Roth-Konforti M., Bauer C., Shabat D., Unprecedented Sensitivity in a Probe for Detection and Imaging of Cathepsin B: Chemiluminescence Microscopy Cell Images of Natively-Expressed Enzyme, Angew. Chem. Int. Ed. 2017, 129, 15839-44.

Schalk I. J. Siderophore-antibiotic conjugates – exploiting iron uptake to deliver drugs into bacteria. Clinical Microbiology and Infection, 2018, 8, 801-802

L. Moynie, S. Milenkovic, G. Malloci, G.L.A. Mislin, V. Gasser, E. Baco, I. J. Schalk, M. Ceccarelli, J. H. Naismith, The complex of ferric-enterobactin with its transporter suggests a multi-step conformationally coupled process of uptake. Nature Com., 2019, 10, 3673

Philipp Klahn, Verena Fetz, Antje Ritter, Wera Collisi, Bettina Hinkelmann, Tatjana Arnold, Werner Tegge, Katharina Rox, Stephan Huttel, Kathrin I. Mohr, Joachim Wink, Marc Stadler, Josef Wissing, Lothar Jansch, Mark Bronstrup, The nuclear export inhibitor aminoratjadone is a potent effector in extracellular-targeted drug conjugates. Chemical Science, 2019, 10, 5197-5210. doi: 10.1039/c8sc05542d

Perraud Q, Cantero P, Munier M, Hoegy F, Zill N, Gasser V, Mislin GLA, Ehret-Sabatier L, Schalk IJ. Phenotypic adaptation of Pseudomonas aeruginosa in the presence of siderophore-antibiotic conjugates during epithelial cell infection. Microorganisms. 2020, 8, 1820.

Perraud Q, Cantero P, Roche B, Gasser V, Normant VP, Kuhn L, Hammann P, Mislin GLA, Ehret-Sabatier L, Schalk IJ. Phenotypic adaptation of Psedomonas aeruginosa by hacking siderophoes produced by other microorganisms. Mol Cell Proteomics. 2020, 19, 589-607.

Lukas Pinkert, Yi-Hui Lai, Carsten Peukert, Sven-Kevin Hotop, Bianka Karge, Lara Marie Schulze, Jörg Grunenberg, and Mark Brönstrup, Antibiotic conjugates with an artificial, MECAM-based siderophore are potent agents against Gram-positive and Gram-negative bacterial pathogens. submitted